SCHEMBL125376

SCHEMBL125376

O=C(O)c1ccc(Oc2ccc(C(c3ccc(Oc4ccc(C(=O)O)c(C(=O)O)c4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
HPSE Q9Y251 1/20 0.48
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
APEX1 P27695 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
TDP1 Q9NUW8 5/20 0.44
LMNA P02545 1/20 0.44
GALK1 P51570 1/20 0.43
CASP6 P55212 1/20 0.43
MCL1 Q07820 1/20 0.43
PLEC Q15149 1/20 0.43
PYGL P06737 3/20 0.42
PYGM P11217 2/20 0.42
DUSP3 P51452 1/20 0.42
PTPN5 P54829 1/20 0.42
PTPN11 Q06124 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405914 1.00 POLB (0.55) POLBHPSEALDH1A1L3MBTL1APEX1
SCHEMBL9153473 0.93 POLB (0.51) POLBHPSEALDH1A1L3MBTL1APEX1
SCHEMBL8923122 0.91 POLB (0.52) POLBHPSEALDH1A1L3MBTL1APEX1
SCHEMBL28490161 0.89 POLB (0.48) POLBHPSEALDH1A1L3MBTL1APEX1
SCHEMBL523943 0.87 POLB (0.58) POLBHPSEALDH1A1L3MBTL1APEX1
SCHEMBL29779713 0.87 POLB (0.51) POLBHPSEALDH1A1TDP1LMNA
SCHEMBL1553762 0.87 KDM4E (0.45) POLBALDH1A1APEX1TDP1CASP6
SCHEMBL1100529 0.87 POLB (0.51) POLBHPSEALDH1A1TDP1LMNA
Pyromellitic Acid SCHEMBL10393987 0.85 ALDH1A1 (0.44) POLBALDH1A1L3MBTL1APEX1CTDSP1
SCHEMBL31525219 0.85 POLB (0.52) POLBHPSEALDH1A1L3MBTL1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166818-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-05-23 US claimed
CN-117736472-A Preparation method of color-adjustable fluorine polyimide film 厦门大学 2024-03-22 CN claimed
CN-117384378-A Photosensitive polyamic acid ester resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2024-01-12 CN claimed
CN-116848177-A Polyimide with low dielectric loss 索尔维特殊聚合物意大利有限公司 2023-10-03 CN claimed
WO-2023029341-A1 COLORLESS TRANSPARENT POLYIMIDE RESIN FILM AND PREPARATION METHOD THEREFOR 山东中柔新材料有限公司 2023-03-09 WO claimed
CN-111234218-B Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2022-12-27 CN claimed
CN-114437350-B Polyimide resin and preparation method and application thereof 波米科技有限公司 2022-09-16 CN claimed
CN-110121496-B Synthesis of reactive intermediates for polyetherimides and uses thereof 高新特殊工程塑料全球技术有限公司 2022-07-12 CN claimed
CN-110669336-B Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2022-06-17 CN claimed
CN-114085379-B Preparation method of flexible colorless transparent polyimide film 富优特(山东)新材料科技有限公司 2022-06-17 CN claimed
WO-1997036837-A1 METHOD OF FORMING A STRIPPABLE POLYIMIDE COATING FOR AN OPTICAL FIBER GALILEO CORPORATION (US) 1997-10-09 WO claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5270438-A Fluorine-containing polyimides and precursors thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-12-14 US claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
WO-1991004300-A1 MISCIBLE BLENDS OF POLYBENZIMIDAZOLES AND POLYAMIDE-IMIDES HAVING FLUORINE-CONTAINING LINKING GROUPS HOECHST CELANESE CORPORATION (US) 1991-04-04 WO claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
US-4925915-A FLUORINE CONTAINING POLYIMIDES HOECHST CELANESE CORP. (US) 1990-05-15 US claimed
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
EP-0142149-A2 Use of fluorine containing polyimides for aligning layers of liquid crystal display devices. HITACHI, LTD. (JP) 1985-05-22 EP claimed