⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14658202 | 1.00 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL13107064 | 0.95 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL125673 | 0.92 | ALDH1A1 (0.57) | — | |
| SCHEMBL130841 | 0.90 | ALDH1A1 (0.61) | — | |
| SCHEMBL127696 | 0.90 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL13923572 | 0.90 | ALDH1A1 (0.61) | — | |
| SCHEMBL8434237 | 0.90 | ALDH1A1 (0.61) | — | |
| SCHEMBL9406721 | 0.89 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL9406588 | 0.89 | CYP1A2 (0.50) | — | |
| SCHEMBL9425995 | 0.89 | SMN1; SMN2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776982-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9713585-B2 | Nail coatings having enhanced adhesion | CREATIVE NAIL DESIGN, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170056313-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | CREATIVE NAIL DESIGN, INC. (US) | 2017-03-02 | — | — | US | disclosed |
| US-20160368889-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | CORSAIR PHARMA INC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160240278-A1 | CONDUCTIVE FILM AND METHOD OF MANUFACTURING THE SAME | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2016-08-18 | — | — | US | disclosed |
| US-9371264-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160067164-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | MUFG BANK LTD. AS AGENT | 2016-03-10 | — | — | US | disclosed |
| US-9005361-B2 | Defoamer compositions for building-product mixtures | EVONIK INDUSTRIES AG (DE) | 2015-04-14 | — | — | US | disclosed |
| US-8895665-B2 | Modified conjugated diene polymer and synthesis method thereof | CHI MEI CORPORATION (TW) | 2014-11-25 | — | — | US | disclosed |
| US-8861916-B2 | Epoxy-functional polysiloxanes, silicone composition, and coated optical fiber | DOW CORNING CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130174760-A1 | DEFOAMER COMPOSITIONS FOR BUILDING-PRODUCT MIXTURES | EVONIK OPERATIONS GMBH (DE) | 2013-07-11 | — | — | US | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8366970-B2 | Method for treating a carbon allotrope | XEROX CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120279575-A1 | FLEXIBLE UNDERWATER PIPE INCLUDING A LAYER INCLUDING A POLYMER RESIN INCLUDING A POLYHEDRAL OLIGOMERIC SILSESQUIOXANE | TECHNIP FRANCE (FR) | 2012-11-08 | — | — | US | disclosed |
| EP-2520570-A1 | AMINOPYRIDINE COMPOUND | Ube Industries, Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20110070438-A1 | Epoxy-Functional Polysiloxanes, Silicone Composition, and Coated Optical Fiber | BAHADUR MANEESH | 2011-03-24 | — | — | US | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |