Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933828 | 0.89 | LPAR3 (0.44) | LPAR3LPAR2LPAR1 | |
| Bromide SCHEMBL28992163 | 0.88 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| SCHEMBL16104469 | 0.85 | RECQL (0.35) | LPAR3LPAR2LPAR1RECQLTSHR | |
| SCHEMBL31106617 | 0.76 | DNM1 (0.37) | LPAR3LPAR2LPAR1TSHRDNM1 | |
| SCHEMBL5185848 | 0.75 | CA1 (0.39) | LPAR3LPAR2LPAR1RECQLTSHR | |
| SCHEMBL26106906 | 0.72 | LPAR3 (0.43) | LPAR3LPAR2LPAR1TSHRGBA1 | |
| SCHEMBL29231575 | 0.72 | LPAR3 (0.43) | LPAR3LPAR2LPAR1TSHRTHRB | |
| SCHEMBL11791100 | 0.72 | LPAR3 (0.43) | LPAR3LPAR2LPAR1TSHRGBA1 | |
| SCHEMBL30634498 | 0.71 | THRB (0.47) | LPAR3LPAR2LPAR1TSHRTHRB | |
| SCHEMBL30634499 | 0.71 | THRB (0.47) | LPAR3LPAR2LPAR1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468612-A1 | HYBRID CARRIERS FOR NUCLEIC ACID CARGO | CureVac AG (DE) | 2019-04-17 | — | — | EP | disclosed |
| EP-3468608-A1 | HYBRID CARRIERS FOR NUCLEIC ACID CARGO | CureVac AG (DE) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017212006-A1 | HYBRID CARRIERS FOR NUCLEIC ACID CARGO | CUREVAC AG (DE) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017212008-A1 | HYBRID CARRIERS FOR NUCLEIC ACID CARGO | CUREVAC AG (DE) | 2017-12-14 | — | — | WO | disclosed |
| EP-2281041-A2 | SILENCING OF CSN5 GENE EXPRESSION USING INTERFERING RNA | Protiva Biotherapeutics Inc. (CA) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009129319-A2 | SILENCING OF CSN5 GENE EXPRESSION USING INTERFERING RNA | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2009-10-22 | — | — | WO | disclosed |