Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthoquinoline SCHEMBL15106 | 0.88 | LMNA (0.69) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL29533982 | 0.88 | LMNA (0.69) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL6826374 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL31286254 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL31141994 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3193877 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL262791 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL6340901 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL3045500 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL5572864 | 0.86 | LMNA (0.67) | LMNACYP3A4KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170059506-A1 | DIAGNOSTIC PRODUCTS HAVING AN ENZYME AND A STABILIZED COENZYME | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2017-03-02 | — | — | US | disclosed |
| US-9528977-B2 | Simplified storage of at least one test element including a dry reagent layer having an enzyme and a stabilized coenzyme | ROCHE DIABETES CARE, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20120241335-A1 | SIMPLIFIED STORAGE OF INTEGRATED SYSTEMS | ROCHE DIABETES CARE, INC. | 2012-09-27 | — | — | US | disclosed |