Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.58 |
| ▸ | WNT3A | P56704 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254915 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL1254914 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL28247961 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL9440127 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL9658034 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL17817131 | 0.98 | LMNA (0.63) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL1255008 | 0.95 | CTNNB1 (0.59) | LMNAHTTSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL3967514 | 0.90 | FAAH (0.70) | LMNAHTTSMN1; SMN2FAAH | |
| SCHEMBL13662381 | 0.90 | FAAH (0.70) | LMNAHTTSMN1; SMN2FAAH | |
| Trifluoroacetic Acid SCHEMBL30785248 | 0.89 | LMNA (0.53) | LMNAHTTSMN1; SMN2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | claimed |
| CN-103347858-B | Process and materials for preparing N-substituted pyridinium compounds | 霍夫曼-拉罗奇有限公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-101516917-B | Functionalized polymers | BRIDGESTONE CORP | 2012-05-09 | — | — | CN | disclosed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | disclosed |
| CN-101516917-A | Functionalized polymers | BRIDGESTONE CORP (JP) | 2009-08-26 | — | — | CN | disclosed |
| EP-1803740-B1 | Method for preparing functionalized polymers | BRIDGESTONE CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| CN-100448846-C | Method for catalytic hydrogenation of acyl pyridine to preparing substituted pyridine compound hydrochlorate | UNIV TSINGHUA (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-101016355-A | Functionalized polymers | BRIDGESTONE CORP (JP) | 2007-08-15 | — | — | CN | disclosed |
| CN-1995017-A | Method for catalytic hydrogenation of acyl pyridine to preparing substituted pyridine compound hydrochlorate | UNIV TSINGHUA (CN) | 2007-07-11 | — | — | CN | disclosed |
| EP-1803740-A1 | Functionalized polymers | Bridgestone Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1335916-A1 | PYRIDYL-SUBSTITUTED TRIAZOLES AS TGF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002040476-A1 | PYRIDYL-SUBSTITUTED TRIAZOLES AS TGF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-05-23 | — | — | WO | disclosed |
| US-5942527-A | Hydrazones, hydrazines, semicarbazones and thiosemicarbazones derived from pyridyl ketones as anticonvulsant drugs and excitatory amino acid antagonists | K & K BIOSCIENCES, INC. (US) | 1999-08-24 | — | — | US | disclosed |