Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.69 |
| ▸ | DHODH | Q02127 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551723 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12181767 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL134060 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12551791 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12551710 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12551756 | 1.00 | KMO (0.69) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL21397887 | 0.98 | KMO (0.67) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12551714 | 0.98 | KMO (0.67) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL12551736 | 0.96 | KMO (0.70) | KMODHODHHDAC8ATMTDP1 | |
| SCHEMBL15159210 | 0.96 | KMO (0.70) | KMODHODHHDAC8ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLCO4C1, GJA1 | KMO 2354/4885DHODH 3617/4885HDAC8 4714/4885 |
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLCO4C1, GJA1 | KMO 2354/4885DHODH 3617/4885HDAC8 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.