SCHEMBL1255288

SCHEMBL1255288

O=C(CC(O)(CC(=O)Oc1ccccc1)C(=O)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.45
ELANE P08246 6/20 0.41
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KMT2A Q03164 1/20 0.37
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL21219096 0.98 CYP19A1 (0.44) CYP19A1ELANEPRSS1PRSS2PRSS3
SCHEMBL28217266 0.92 PRSS1 (0.41) CYP19A1ELANEPRSS1PRSS2PRSS3
Ammonia Solution, Strong SCHEMBL21219126 0.85 CYP19A1 (0.45) CYP19A1ELANEPRSS1PRSS2PRSS3
SCHEMBL7121311 0.82 KMT2A (0.50) ELANEL3MBTL1TDP1ALDH1A1MAPT
SCHEMBL6600932 0.82 ALDH1A1 (0.52) CYP19A1L3MBTL1TDP1ALDH1A1MAPT
SCHEMBL27589888 0.81 ALDH1A1 (0.50) CYP19A1L3MBTL1TDP1ALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL21219130 0.81 ALDH1A1 (0.50) CYP19A1L3MBTL1TDP1ALDH1A1MAPT
SCHEMBL28105443 0.81 ALDH1A1 (0.50) CYP19A1L3MBTL1TDP1ALDH1A1MAPT
SCHEMBL28159769 0.80 CYP19A1 (0.41) CYP19A1ELANEPRSS1PRSS2PRSS3
SCHEMBL28836794 0.79 CYP19A1 (0.46) CYP19A1ELANEPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250312270-A1 READY-TO-INFUSE PHENYLEPHRINE COMPOSITIONS AMNEAL EU, LIMITED (IE) 2025-10-09 US disclosed
EP-4574870-A1 BLOCKED POLYISOCYANATE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
US-20250025409-A1 READY-TO-INFUSE PHENYLEPHRINE COMPOSITIONS AMNEAL EU, LIMITED (IE) 2025-01-23 US disclosed
US-20240351957-A1 ADMIXTURE TO CONTROL THE HEAT FLOW FROM MINERAL BINDER COMPOSITIONS, MINERAL BINDER COMPOSITIONS, AND PRODUCTION METHOD THEREOF SIKA TECHNOLOGY AG (CH) 2024-10-24 US disclosed
WO-2024175602-A1 LIGHTWEIGHT CEMENTITIOUS COMPOSITION HAVING KINETIC REGULATOR SIKA TECHNOLOGY AG (CH) 2024-08-29 WO disclosed
WO-2024175610-A1 METHODS FOR THE APPLICATION IN THICK LAYER OF CEMENTITIOUS COMPOSITIONS COMPRISING KINETIC REGULATOR SIKA TECHNOLOGY AG (CH) 2024-08-29 WO disclosed
EP-4417588-A1 LIGHTWEIGHT CEMENTITIOUS COMPOSITION HAVING KINETIC REGULATOR Sika Technology AG (CH) 2024-08-21 EP disclosed
EP-4417587-A1 METHODS FOR THE APPLICATION IN THICK LAYER OF CEMENTITIOUS COMPOSITIONS COMPRISING KINETIC REGULATOR Sika Technology AG (CH) 2024-08-21 EP disclosed
EP-4396150-A1 ADMIXTURE TO CONTROL THE HEAT FLOW FROM MINERAL BINDER COMPOSITIONS, MINERAL BINDER COMPOSITIONS, AND PRODUCTION METHOD THEREOF Sika Technology AG (CH) 2024-07-10 EP disclosed
CN-117677595-A Additive for controlling heat flow from mineral binder composition, mineral binder composition and method for producing the same SIKA技术股份公司 2024-03-08 CN disclosed
US-5702635-A COATING ALKALI METAL SALT OF A PERCARBONATE WITH HYDROPHOBIC ESTER OF CITRIC ACID THE PROCTER & GAMBLE COMPANY (US) 1997-12-30 US disclosed
EP-0514067-B1 Cosmetic composition UNILEVER PLC (GB) 1997-08-27 EP disclosed
CN-1131407-A Granglar laundry bleaching composition PROCTER & GAMBLE (US) 1996-09-18 CN disclosed
WO-1996008253-A1 HYDROCODONE COMPOSITIONS ALZA CORPORATION (US) 1996-03-21 WO disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
WO-1995008509-A1 GRANULAR LAUNDRY BLEACHING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1995-03-30 WO disclosed
EP-0644258-A1 Granular laundry bleaching composition THE PROCTER & GAMBLE COMPANY (US) 1995-03-22 EP disclosed
US-5244665-A Citric acid triesters to repair UV damage to skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-09-14 US disclosed
EP-0517371-A2 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1992-12-09 EP disclosed
EP-0514067-A1 Cosmetic composition UNILEVER PLC (GB) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312270-A1 READY-TO-INFUSE PHENYLEPHRINE COMPOSITIONS REN, PEF1, AVPR2 CYP19A1 765/4885ELANE 419/4885PRSS1 1610/4885
US-20250025409-A1 READY-TO-INFUSE PHENYLEPHRINE COMPOSITIONS REN, PEF1, AVPR2 CYP19A1 765/4885ELANE 419/4885PRSS1 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.