Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 6/20 | 0.55 |
| ▸ | PLK1 | P53350 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756485 | 0.85 | PLK1 (0.57) | TRPV1PLK1 | |
| SCHEMBL22556340 | 0.82 | TRPV1 (0.84) | TRPV1KMT2ARARBPLK1MAPT | |
| SCHEMBL8361576 | 0.81 | TRPV1 (0.69) | TRPV1NPC1RAB9APLK1KDM4E | |
| SCHEMBL8642579 | 0.81 | TRPV1 (0.61) | TRPV1KMT2ANPC1RAB9ARARB | |
| SCHEMBL8391675 | 0.80 | TRPV1 (0.56) | TRPV1PLK1KDM4E | |
| SCHEMBL20284428 | 0.79 | TRPV1 (0.70) | TRPV1NPC1RAB9ARARBPLK1 | |
| SCHEMBL12440862 | 0.79 | TRPV1 (0.69) | TRPV1NPC1RAB9APLK1KDM4E | |
| SCHEMBL4751447 | 0.79 | TRPV1 (0.69) | TRPV1NPC1RAB9APLK1KDM4E | |
| SCHEMBL27052325 | 0.78 | PLK1 (0.61) | TRPV1PLK1KDM4EMAPT | |
| SCHEMBL1834503 | 0.78 | TRPV1 (0.68) | TRPV1NPC1RAB9APLK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | TRPV1 2881/4885KMT2A 563/4885NPC1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.