Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9887459 | 0.95 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1CYP17A1CHEK1 | |
| SCHEMBL9887001 | 0.94 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1CYP17A1MAPT | |
| SCHEMBL12554398 | 0.92 | CYP11B1 (0.39) | CYP11B1CHEK1MAPTCYP3A4METAP2 | |
| SCHEMBL9887607 | 0.91 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1CYP17A1CHEK1 | |
| SCHEMBL12554999 | 0.89 | CYP2A6 (0.44) | CYP11B1CYP11B2CYP19A1CYP17A1CHEK1 | |
| SCHEMBL9887562 | 0.89 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP17A1CHEK1 | |
| SCHEMBL9886995 | 0.87 | TNF (0.41) | CYP11B1CYP11B2CYP19A1CYP17A1MAPT | |
| SCHEMBL9886989 | 0.85 | IMPDH2 (0.45) | CHEK1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL15860041 | 0.84 | CYP11B1 (0.41) | CYP11B1CYP11B2CYP19A1CYP17A1CHEK1 | |
| SCHEMBL9887334 | 0.83 | MEN1 (0.38) | CYP11B1CYP11B2CHEK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068204-A1 | BENZO[C]CARBAZOLE COMPOUND THAT HAS SUBSTITUENT BEARING PYRIDINE RING, AND ORGANIC ELECTROLUMINESCENT ELEMENT | JNC株式会社 (JP) | 2011-06-09 | — | — | WO | disclosed |