Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12554358 | 0.92 | CYP11B1 (0.45) | CYP11B1DHODHCYP3A4CYP1A2POLB | |
| SCHEMBL12554999 | 0.89 | CYP2A6 (0.44) | CYP11B1DHODHCYP3A4CYP2C19CHEK1 | |
| SCHEMBL9887459 | 0.88 | CYP11B1 (0.40) | CYP11B1DHODHCYP3A4MAPTCHEK1 | |
| SCHEMBL9973717 | 0.88 | METAP2 (0.45) | CYP11B1CYP3A4CYP1A2POLBCYP2C9 | |
| SCHEMBL9887001 | 0.87 | CYP11B1 (0.44) | CYP11B1DHODHCYP3A4CYP1A2POLB | |
| SCHEMBL9887607 | 0.84 | CYP11B1 (0.53) | CYP11B1MAPTCHEK1CYP2A6 | |
| SCHEMBL16159213 | 0.83 | PIM1 (0.39) | CHEK1PIM1 | |
| SCHEMBL9973767 | 0.83 | CYP2A6 (0.45) | CYP3A4CYP1A2POLBCYP2C9CYP2C19 | |
| SCHEMBL24345161 | 0.82 | CYP19A1 (0.42) | CYP11B1DHODHMAPTCYP2A6METAP2 | |
| SCHEMBL9887562 | 0.82 | CYP11B1 (0.51) | CYP11B1CYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068204-A1 | BENZO[C]CARBAZOLE COMPOUND THAT HAS SUBSTITUENT BEARING PYRIDINE RING, AND ORGANIC ELECTROLUMINESCENT ELEMENT | JNC株式会社 (JP) | 2011-06-09 | — | — | WO | disclosed |