SCHEMBL1255448

SCHEMBL1255448

CCCCC=C(O)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.47
GRIK1 P39086 1/20 0.46
FAAH O00519 3/20 0.41
SOAT1 P35610 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.39
CNR1 P21554 1/20 0.38
KDM4E B2RXH2 2/20 0.37
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831469 1.00 EP300 (0.47) EP300GRIK1FAAHSOAT1CYP1A2
SCHEMBL6557190 0.93 EP300 (0.55) EP300FAAHSOAT1CYP1A2CYP2C19
SCHEMBL23674866 0.91 EP300 (0.59) EP300FAAHSOAT1CYP1A2CYP2C19
SCHEMBL367396 0.86
SCHEMBL3221896 0.86
SCHEMBL51444 0.81 EP300 (0.56) EP300GRIK1FAAHCYP1A2CYP2C19
SCHEMBL3015069 0.81 EP300 (0.56) EP300GRIK1FAAHCYP1A2CYP2C19
SCHEMBL29134998 0.79 EP300 (0.43) EP300GRIK1FAAHSOAT1CYP1A2
SCHEMBL7115099 0.79 EP300 (0.48) EP300GRIK1FAAHCYP1A2CYP2C19
SCHEMBL19980211 0.79 EP300 (0.43) EP300GRIK1FAAHSOAT1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622842-B Azacyclopropane and N- vinyl acetamides or the synthetic method with N- methyl-Nvinylacetamide copolymers 浙江理工大学 2018-05-22 CN claimed
CN-106366257-A Low-sensitivity anti-mud crossed branched chain type polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2017-02-01 CN disclosed
CN-102066486-B Gel composition, method for preparing the same, and impact-resistant absorbing material using the same 3M INNOVATIVE PROPERTIES CO 2013-08-14 CN disclosed
US-8461237-B2 Gel composition, method of preparing the same, and impact resistant absorbing material using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-11 US disclosed
CN-102516094-A Production method of butyl amide ethenol NINGXIA DONGKE PETRIFACTION CO LTD 2012-06-27 CN disclosed
CN-102349364-A Electromagnetic wave shielding gel-like composition 3M INNOVATIVE PROPERTIES CO 2012-02-08 CN disclosed
CN-102066486-A Gel composition, method for preparing the same, and impact-resistant absorbing material using the same 3M INNOVATIVE PROPERTIES CO 2011-05-18 CN disclosed
US-20110097585-A1 GEL COMPOSITION, METHOD OF PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2011-04-28 US disclosed
EP-2285900-A2 GEL COMPOSITION, METHOD FOR PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME 3M Innovative Properties Company (US) 2011-02-23 EP disclosed
WO-2009134694-A2 GEL COMPOSITION, METHOD FOR PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-05 WO disclosed