Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674866 | 0.98 | EP300 (0.59) | EP300FAAHSOAT1CYP1A2CYP2C19 | |
| SCHEMBL1255448 | 0.93 | EP300 (0.47) | EP300FAAHSOAT1CYP1A2CYP2C19 | |
| SCHEMBL5831469 | 0.93 | EP300 (0.47) | EP300FAAHSOAT1CYP1A2CYP2C19 | |
| SCHEMBL367396 | 0.84 | — | — | |
| SCHEMBL3221896 | 0.84 | — | — | |
| SCHEMBL3849978 | 0.82 | EP300 (0.65) | EP300FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL3985350 | 0.82 | EP300 (0.65) | EP300FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL3682579 | 0.80 | EP300 (0.69) | EP300FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL3794261 | 0.80 | EP300 (0.69) | EP300FAAHCYP1A2CYP2C19KMT2A | |
| SCHEMBL1151027 | 0.80 | EP300 (0.69) | EP300FAAHCYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918547-B1 | RADIOLABELED ANNEXINS | NEORX CORP (US) | 2004-03-10 | — | — | EP | claimed |