Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769345 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRNOS1FBP1 | |
| SCHEMBL29769344 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRNOS1FBP1 | |
| SCHEMBL28343612 | 0.84 | LMNA (0.38) | ALDH1A1HSD17B10NPC1RAB9AL3MBTL1 | |
| SCHEMBL28343610 | 0.84 | LMNA (0.38) | ALDH1A1HSD17B10NPC1RAB9AL3MBTL1 | |
| SCHEMBL28351134 | 0.84 | LMNA (0.54) | ALDH1A1HSD17B10NPC1RAB9AL3MBTL1 | |
| SCHEMBL28351133 | 0.84 | LMNA (0.54) | ALDH1A1HSD17B10NPC1RAB9AL3MBTL1 | |
| SCHEMBL28343083 | 0.83 | SMN1; SMN2 (0.66) | ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL28882158 | 0.83 | SMN1; SMN2 (0.66) | ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL28342419 | 0.82 | NR4A1 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1PKM | |
| SCHEMBL28342420 | 0.82 | NR4A1 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183326-B2 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION (JP) | 2012-05-22 | — | — | US | claimed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | claimed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | claimed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1803740-B1 | Method for preparing functionalized polymers | BRIDGESTONE CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1803740-A1 | Functionalized polymers | Bridgestone Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |