SCHEMBL12558271

SCHEMBL12558271

CCCc1cccc[n+]1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.41
EEF2K O00418 2/20 0.41
EEF2 P13639 2/20 0.41
MEN1 O00255 1/20 0.41
PLK4 O00444 1/20 0.41
JAK2 O60674 1/20 0.41
EGFR P00533 1/20 0.41
TYK2 P29597 1/20 0.41
FLT3 P36888 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
ITK Q08881 1/20 0.41
PIM2 Q9P1W9 1/20 0.41
KCNH2 Q12809 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5297200 0.86 EEF2K (0.50) CYP2D6CYP2C19EEF2KEEF2MEN1
SCHEMBL5300312 0.86 EEF2K (0.50) CYP2D6CYP2C19EEF2KEEF2MEN1
Hydrochloric Acid SCHEMBL16144878 0.85 MEN1 (0.49) CYP2D6CYP2C19TP53EEF2KEEF2
Hydrochloric Acid SCHEMBL1072630 0.85 MEN1 (0.49) CYP2D6CYP2C19TP53EEF2KEEF2
Bromide SCHEMBL11692702 0.83 TP53 (0.48) CYP2D6CYP2C19TP53EEF2KEEF2
SCHEMBL10730872 0.81 TDP1 (0.48) CYP2D6CYP2C19MEN1KMT2AKCNH2
SCHEMBL12558267 0.80 KDM4E (0.38) TP53MEN1KMT2AKCNH2ALDH1A1
SCHEMBL9253184 0.79 RAB9A (0.38) CYP2D6CYP2C19MEN1KMT2AKCNH2
SCHEMBL19700931 0.77 CYP2D6 (0.43) CYP2D6CYP2C19TP53EEF2KEEF2
Hydrochloric Acid SCHEMBL11725090 0.77 KDM4E (0.45) CYP2D6CYP2C19MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
US-20240069441-A1 COMPOSITION FOR RESIST UNDERLYING FILM FORMATION NISSAN CHEMICAL CORPORATION (JP) 2024-02-29 US disclosed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
US-20230168582-A1 COMPOSITION FOR FORMING RESIST UNDERLYING FILM NISSAN CHEMICAL CORPORATION (JP) 2023-06-01 US disclosed
US-20230152700-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-05-18 US disclosed
US-8864894-B2 Resist underlayer film forming composition containing silicone having onium group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP SRR, KDM2B, MSR1 CYP2D6 3670/4885CYP2C19 2339/4885TP53 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.