Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940855 | 1.00 | HTT (0.52) | HTTHCAR2ATMALDH1A1TP53 | |
| SCHEMBL1904263 | 1.00 | HTT (0.52) | HTTHCAR2ATMALDH1A1TP53 | |
| SCHEMBL1255842 | 0.91 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1TP53 | |
| SCHEMBL4171829 | 0.91 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1TP53 | |
| SCHEMBL1255835 | 0.91 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1TP53 | |
| SCHEMBL9240695 | 0.89 | HCAR2 (0.57) | HTTHCAR2ATMALDH1A1MAPT | |
| SCHEMBL13386028 | 0.89 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1KEAP1 | |
| SCHEMBL9242318 | 0.89 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1KEAP1 | |
| SCHEMBL9242308 | 0.89 | HCAR2 (0.54) | HTTHCAR2ATMALDH1A1KEAP1 | |
| SCHEMBL9240703 | 0.89 | HCAR2 (0.57) | HTTHCAR2ATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096132-B | Fluorine-containing polyaspartic acid ester resin and synthesis method thereof | 深圳飞扬骏研新材料股份有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-109207039-B | Fluorine modified asparagus polyurea coating and preparation method thereof | 深圳飞扬骏研新材料股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| WO-2019143560-A9 | METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-12 | — | — | WO | claimed |
| WO-2019143560-A1 | METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-07-25 | — | — | WO | claimed |
| US-20190111016-A1 | METHODS OF TREATING MUSCLE AND LIVER DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-18 | — | — | US | claimed |
| WO-2017147505-A1 | METHODS OF TREATING MUSCLE AND LIVER DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-31 | — | — | WO | claimed |
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | claimed |
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| JP-62099720-A | — | — | None | — | — | JP | disclosed |
| JP-62106432-A | — | — | None | — | — | JP | disclosed |
| CN-109096132-B | Fluorine-containing polyaspartic acid ester resin and synthesis method thereof | 深圳飞扬骏研新材料股份有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-109207039-B | Fluorine modified asparagus polyurea coating and preparation method thereof | 深圳飞扬骏研新材料股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| WO-2019143560-A9 | METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019143560-A1 | METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-07-25 | — | — | WO | disclosed |
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| JP-S62106432-A | CONTACT LENS MATERIAL | TOOMEE SANGYO KK | 1987-05-16 | — | — | JP | disclosed |
| JP-S6299720-A | CONTACT LENS MATERIAL | TOOMEE SANGYO KK | 1987-05-09 | — | — | JP | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4075237-A | Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof | GEIGY CHEMICAL CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190111016-A1 | METHODS OF TREATING MUSCLE AND LIVER DISORDERS | CKMT1A; CKMT1B, CPT1B, GLS2 | HTT 1964/4885HCAR2 2186/4885ATM 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.