SCHEMBL1255835

SCHEMBL1255835

O=C(O)/C=C/C(=O)OCC(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 12/20 0.54
HTT P42858 1/20 0.45
TSHR P16473 2/20 0.39
TP53 P04637 2/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
ATM Q13315 1/20 0.34
FABP7 O15540 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1255842 1.00 HCAR2 (0.54) HCAR2HTTTSHRTP53EGLN1
SCHEMBL4171829 1.00 HCAR2 (0.54) HCAR2HTTTSHRTP53EGLN1
SCHEMBL1255837 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL1904263 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL940855 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL4164061 0.83 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL26362994 0.83 HCAR2 (0.55) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL9242308 0.81 HCAR2 (0.54) HCAR2HTTATMALDH1A1KDM4E
SCHEMBL9242318 0.81 HCAR2 (0.54) HCAR2HTTATMALDH1A1KDM4E
SCHEMBL9240695 0.81 HCAR2 (0.57) HCAR2HTTATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096132-B Fluorine-containing polyaspartic acid ester resin and synthesis method thereof 深圳飞扬骏研新材料股份有限公司 2021-04-16 CN claimed
CN-109207039-B Fluorine modified asparagus polyurea coating and preparation method thereof 深圳飞扬骏研新材料股份有限公司 2021-01-05 CN claimed
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US claimed
US-11945890-B2 Fluorinated PVC copolymer compositions for increased ultraviolet protection Mexichem Specialty Resins Inc. (US) 2024-04-02 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
EP-4249519-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. (US) 2023-09-27 EP disclosed
CN-109096132-B Fluorine-containing polyaspartic acid ester resin and synthesis method thereof 深圳飞扬骏研新材料股份有限公司 2021-04-16 CN disclosed
CN-109207039-B Fluorine modified asparagus polyurea coating and preparation method thereof 深圳飞扬骏研新材料股份有限公司 2021-01-05 CN disclosed
US-9722240-B2 Electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators ACEP INC. (CA) 2017-08-01 US disclosed
US-7879492-B2 redox system; lithium batteries; nontoxic; improved electroconductivity ACEP INC. (CA) 2011-02-01 US disclosed
US-20100237298-A1 NEW ELECTRODE MATERIALS DERIVED FROM POLYQUINONIC IONIC COMPOUNDS AND THEIR USE IN ELECTROCHEMICAL GENERATORS ARMAND MICHEL 2010-09-23 US disclosed
US-20040202930-A1 New electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators NATIONAL SCIENCE FOUNDATION 2004-10-14 US disclosed
US-6743877-B1 ANIONIC REDOX MATERIALS; HIGHLY HETEROCONJUGATED SYSTEMS ACEP INC (CA) 2004-06-01 US disclosed
US-20030118877-A1 New electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators ARMAND MICHEL (CA) 2003-06-26 US disclosed
EP-0448978-B1 Material for contact lenses and contact lenses prepared therefrom HOYA CORP (JP) 1995-02-01 EP disclosed
US-5142009-A Crosslinked blend of fumaric acid diesters TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
EP-0448978-A2 Material for contact lenses and contact lenses prepared therefrom HOYA CORPORATION (JP) 1991-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040202930-A1 New electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators HTT, ATXN10, ATXN2 HCAR2 3793/4885HTT 1/4885TSHR 4457/4885
US-20100237298-A1 NEW ELECTRODE MATERIALS DERIVED FROM POLYQUINONIC IONIC COMPOUNDS AND THEIR USE IN ELECTROCHEMICAL GENERATORS HTT, ATXN10, ATXN2 HCAR2 3793/4885HTT 1/4885TSHR 4457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.