SCHEMBL4171829

SCHEMBL4171829

O=C(O)/C=C\C(=O)OCC(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 12/20 0.54
HTT P42858 1/20 0.45
TSHR P16473 2/20 0.39
TP53 P04637 2/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
ATM Q13315 1/20 0.34
FABP7 O15540 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1255835 1.00 HCAR2 (0.54) HCAR2HTTTSHRTP53EGLN1
SCHEMBL1255842 1.00 HCAR2 (0.54) HCAR2HTTTSHRTP53EGLN1
SCHEMBL1255837 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL1904263 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL940855 0.91 HTT (0.52) HCAR2HTTTSHRTP53ATM
SCHEMBL4164061 0.83 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL26362994 0.83 HCAR2 (0.55) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL9242308 0.81 HCAR2 (0.54) HCAR2HTTATMALDH1A1KDM4E
SCHEMBL9242318 0.81 HCAR2 (0.54) HCAR2HTTATMALDH1A1KDM4E
SCHEMBL9240695 0.81 HCAR2 (0.57) HCAR2HTTATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059387-A Multi-layer composite antibacterial medical packaging bag and preparation method thereof 江苏帕科医疗股份有限公司 2025-05-30 CN claimed
EP-1194479-B1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES PROMETIC BIOSCIENCES INC (CA) 2004-02-18 EP claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-6573307-B1 Make particles by anaerobic reaction of a water- insoluble solution of organic compounds comprising (a) a monomer selected from C2-4 alkylene glycol esters of a C3-6 acrylic acid and a divinyl benzene; (b) a polyfluorinated vinyl PROMETIC BIOSCIENCES, INC. (CA) 2003-06-03 US claimed
EP-1194479-A1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES Prometic Biosciences Inc. (CA) 2002-04-10 EP claimed
WO-2000077081-A1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES PROMETIC BIOSCIENCES INC. (CA) 2000-12-21 WO claimed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP claimed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US claimed
CN-120059387-A Multi-layer composite antibacterial medical packaging bag and preparation method thereof 江苏帕科医疗股份有限公司 2025-05-30 CN disclosed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN disclosed
CN-104080780-B Derivative, its preparation method and its purposes as solvent additive of the meldrum's acid of fluorination 索尔维公司 2018-04-13 CN disclosed
CN-104704067-B Smooth self-lubricating polymer surface 哈佛学院院长及董事 2018-04-10 CN disclosed
CN-104428941-B The carbonyls of fluorination comprising three keys, its manufacture method and application thereof 索尔维公司 2017-10-13 CN disclosed
EP-0506067-A1 Monodispersed thermoplastic acrylic polymers in supercritical fluids UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-09-30 EP disclosed
EP-0481431-A2 Pressurized fluid composition and process for making same UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION, Three Cristina Centre (US) 1992-04-22 EP disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed