Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13072420 | 0.93 | ELANE (0.39) | HSD11B1KLK7KLK14KLK5ACVR1 | |
| SCHEMBL950741 | 0.89 | ELANE (0.45) | HSD11B1ELANEKDM4EL3MBTL1C1R | |
| SCHEMBL950869 | 0.88 | C1R (0.43) | HSD11B1PTGS1PTGS2KDM4EL3MBTL1 | |
| SCHEMBL12559403 | 0.87 | KDM4E (0.39) | KLK7KLK14KLK5PTGS1PTGS2 | |
| SCHEMBL13072499 | 0.86 | CARM1 (0.34) | HSD11B1PTGS1PTGS2CARM1ELANE | |
| SCHEMBL12560144 | 0.86 | PTGS2 (0.33) | HSD11B1PTGS1PTGS2CARM1KDM4E | |
| SCHEMBL950464 | 0.83 | C1R (0.42) | ELANEKDM4EL3MBTL1C1R | |
| SCHEMBL949711 | 0.83 | APEX1 (0.45) | HSD11B1PTGS1PTGS2ELANEKDM4E | |
| SCHEMBL4080657 | 0.82 | ELANE (0.38) | PTGS1PTGS2CARM1ELANEKDM4E | |
| SCHEMBL14495253 | 0.82 | KDM4E (0.33) | PTGS1PTGS2CARM1ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937664-B1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-06-15 | — | — | EP | disclosed |