Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18753291 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL3660657 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL167986 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL19386605 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL241401 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL1384556 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL30977108 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL25162057 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL31494657 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL17963025 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183326-B2 | A living polymer endcapped with an azine compound; uniformly distributed reinforcing particulate fillers; tire treads with increased balance between rolling resistance and traction | BRIDGESTONE CORPORATION (JP) | 2012-05-22 | — | — | US | claimed |
| CN-101516917-B | Functionalized polymers | BRIDGESTONE CORP | 2012-05-09 | — | — | CN | claimed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | claimed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | claimed |
| CN-106715479-B | Catalyst for polymerization of conjugated diene, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and composition containing same | 宇部兴产株式会社 | 2019-07-23 | — | — | CN | disclosed |
| CN-101516917-B | Functionalized polymers | BRIDGESTONE CORP | 2012-05-09 | — | — | CN | disclosed |
| US-7879952-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2011-02-01 | — | — | US | disclosed |
| CN-101516917-A | Functionalized polymers | BRIDGESTONE CORP (JP) | 2009-08-26 | — | — | CN | disclosed |
| EP-1803740-B1 | Method for preparing functionalized polymers | BRIDGESTONE CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1803740-A1 | Functionalized polymers | Bridgestone Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070149717-A1 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |