Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660657 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL1256130 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL167986 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL19386605 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL241401 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL25162057 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL31494657 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL17963025 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL9768928 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A | |
| SCHEMBL20412779 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1TOP2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106959589-A | Colourama resist or organic insulating film remover composition | 东友精细化工有限公司 | 2017-07-18 | — | — | CN | claimed |
| CN-103833561-B | The N-arylation method of alkane amine | HENGYANG NORMAL UNIVERSITY (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-103833561-A | Method for N-arylation of alkane amine | UNIV HENGYANG NORMAL | 2014-06-04 | — | — | CN | claimed |
| JP-4709741-B2 | — | — | 2011-06-22 | — | — | JP | claimed |
| CN-100393701-C | Process for preparing pyridine-substituted amino ketal derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-06-11 | — | — | CN | claimed |
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | claimed |
| JP-2007501701-A | — | — | 2007-02-01 | — | — | JP | claimed |
| CN-1845789-A | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL FRANCE (FR) | 2006-10-11 | — | — | CN | claimed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | claimed |
| CN-1747932-A | Process for preparing pyridine substituted amino ketal derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-03-15 | — | — | CN | claimed |
| EP-1601648-A2 | PROCESS FOR PREPARING PYRIDINE-SUBSTITUTED AMINO KETAL DERIVATIVES | Sanofi-Aventis Deutschland GmbH (DE) | 2005-12-07 | — | — | EP | claimed |
| US-6916934-B2 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-07-12 | — | — | US | claimed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | claimed |
| WO-2004072026-A2 | PROCESS FOR PREPARING PYRIDINE-SUBSTITUTED AMINO KETAL DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | claimed |
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-12 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-4695256-A2 | ERBB2 INHIBITORS | Cogent Biosciences, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2025121436-A1 | BICYCLIC HETEROCYCLIC COMPOUND AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学クロップ＆ライフソリューション株式会社 | 2025-06-12 | — | — | WO | disclosed |
| US-4402955-A | ZWITTERIONS; GRAMNEGATIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1983-09-06 | — | — | US | disclosed |
| US-4379787-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | KMO, PKN1, PKN2 | KDM4E 68/4885ALDH1A1 234/4885TOP2A 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.