Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19386605 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL167986 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL1256130 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL3660657 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL1384556 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL25162057 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL17963025 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL9768928 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL31494657 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL21238884 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1TOP2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363923-B1 | RHODIUM AND IRIDIUM COMPLEXES | MERCK PATENT GMBH (DE) | 2009-04-01 | — | — | EP | claimed |
| US-12635401-B2 | Metal complexes | UDC Ireland (IE) | 2026-05-19 | — | — | US | disclosed |
| US-20260070936-A1 | METAL COMPLEXES | UDC IRELAND LTD (IE) | 2026-03-12 | — | — | US | disclosed |
| EP-4069709-B1 | METAL COMPLEXES | UDC IRELAND LTD (IE) | 2025-04-23 | — | — | EP | disclosed |
| US-12250871-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2025-03-11 | — | — | US | disclosed |
| US-20240260448-A1 | Metal Complexes | UDC IRELAND LIMITED (IE) | 2024-08-01 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-11404649-B2 | Electroluminescent bridged metal complexes for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-08-02 | — | — | US | disclosed |
| US-20220209141-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
| US-7498398-B2 | Thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-03-03 | — | — | US | disclosed |
| US-20080228012-A1 | Reducing esters or lactones with hydrogen gas in presence of ruthenium catalyst; high yield and high catalytic efficiency under an industrially advantageous condition of relatively low hydrogen pressure and low reaction temperature | TAKASAGO INTERNATIONAL CORPORATION | 2008-09-18 | — | — | US | disclosed |
| US-20080027220-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20070225470-A1 | Thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-09-27 | — | — | US | disclosed |
| US-20070219330-A1 | Amide initiators | WARWICK EFFECT POLYMERS LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |
| US-7247761-B2 | Method for the production of aryl-aryl coupled compounds | MERCK PATENT GMBH (DE) | 2007-07-24 | — | — | US | disclosed |
| EP-1537161-B1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS (DE) | 2006-03-29 | — | — | EP | disclosed |
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| EP-1537161-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | Covion Organic Semiconductors GmbH (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022626-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070936-A1 | METAL COMPLEXES | SCO2, CBR1, CORO1C | KDM4E 4498/4885ALDH1A1 2087/4885TOP2A 3872/4885 |
| US-12635401-B2 | Metal complexes | SCO2, SOD1, NR4A1 | KDM4E 3445/4885ALDH1A1 2069/4885TOP2A 2604/4885 |
| US-12250871-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | KDM4E 3628/4885ALDH1A1 3790/4885TOP2A 4088/4885 |
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | KDM4E 4474/4885ALDH1A1 1713/4885TOP2A 2545/4885 |
| US-20080228012-A1 | Reducing esters or lactones with hydrogen gas in presence of ruthenium catalyst; high yield and high catalytic efficiency under an industrially advantageous condition of relatively low hydrogen pressure and low reaction temperature | LPXN, LIPE, MLX | KDM4E 2963/4885ALDH1A1 1512/4885TOP2A 4285/4885 |
| US-11404649-B2 | Electroluminescent bridged metal complexes for use in electronic devices | MCOLN2, MCOLN1, NCLN | KDM4E 4201/4885ALDH1A1 1380/4885TOP2A 3174/4885 |
| US-20080027220-A1 | Metal Complexes | AP1M1, SOD1, AP1G1 | KDM4E 3323/4885ALDH1A1 363/4885TOP2A 3240/4885 |
| US-20220209141-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | KDM4E 3628/4885ALDH1A1 3790/4885TOP2A 4088/4885 |
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | TYR, AHR, ARSA | KDM4E 1022/4885ALDH1A1 366/4885TOP2A 4205/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | KDM4E 4260/4885ALDH1A1 1631/4885TOP2A 3261/4885 |
| US-20240260448-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.