E1501

E1501

SCHEMBL1256238

CC(=O)OCc1ccccc1.N

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.96
TDP1 Q9NUW8 3/20 0.59
MAPK1 P28482 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
KMT2A Q03164 1/20 0.59
IDH1 O75874 1/20 0.54
LMNA P02545 3/20 0.53
HCAR2 Q8TDS4 1/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MAOB P27338 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E1501 SCHEMBL43745 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14031569 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28201296 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL901210 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL18954294 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL30579458 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28928069 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL183528 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14334870 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL27585125 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9243072-B2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2016-01-26 US disclosed
US-9150665-B2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2015-10-06 US disclosed
CN-104755456-A Method for producing optically active bicyclic [gamma]-amino acid derivative DAIICHI SANKYO CO LTD 2015-07-01 CN disclosed
US-9040684-B2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2015-05-26 US disclosed
US-9040683-B2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2015-05-26 US disclosed
US-9040685-B2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2015-05-26 US disclosed
US-8816066-B2 Cellulose interpolymers and methods of oxidation EASTMAN CHEMICAL COMPANY (US) 2014-08-26 US disclosed
US-20130203982-A1 CELLULOSE INTERPOLYMERS AND METHOD OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2013-08-08 US disclosed
US-20130131333-A1 CELLULOSE INTERPOLYMERS AND METHOD OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2013-05-23 US disclosed
US-20130116427-A1 CELLULOSE INTERPOLYMERS AND METHOD OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2013-05-09 US disclosed
EP-2532683-A2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2012-12-12 EP disclosed
EP-2532684-A2 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY (US) 2012-12-12 EP disclosed
CN-1886427-B Cellulose interpolymers and methods of oxidation EASTMAN CHEM CO 2012-05-23 CN disclosed
CN-102276732-A Cellulose interpolymers and methods of oxidation 2011-12-14 CN disclosed
US-20110098464-A1 CELLULOSE INTERPOLYMERS AND METHODS OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2011-04-28 US disclosed
US-7879994-B2 For use as binder resins and drug delivery agents; bioavailability EASTMAN CHEMICAL COMPANY (US) 2011-02-01 US disclosed
CN-1886427-A Cellulose interpolymers and methods of oxidation EASTMAN CHEM CO (US) 2006-12-27 CN disclosed
EP-1689787-A2 CELLULOSE INTERPOLYMERS AND METHOD OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2006-08-16 EP disclosed
US-20050192434-A1 Cellulose interpolymers and method of oxidation EASTMAN CHEMICAL COMPANY 2005-09-01 US disclosed
WO-2005054297-A2 CELLULOSE INTERPOLYMERS AND METHOD OF OXIDATION EASTMAN CHEMICAL COMPANY (US) 2005-06-16 WO disclosed