E1501

E1501

SCHEMBL43745

CC(=O)OCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
TDP1 Q9NUW8 3/20 0.61
MAPK1 P28482 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A3 Q01959 1/20 0.61
KMT2A Q03164 1/20 0.61
IDH1 O75874 1/20 0.55
LMNA P02545 3/20 0.55
HCAR2 Q8TDS4 1/20 0.55
MAOB P27338 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E1501 SCHEMBL901210 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14031569 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28201296 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL30579458 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL183528 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL1256238 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL18954294 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28928069 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14334870 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL27655685 0.98 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 409927 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119187558-A Preparation method of carbon-coated porous tin 烟台力华电源科技有限公司 2024-12-27 CN claimed
CN-119191227-A Method for separating hydrogen chloride from tail gas of process for preparing 1, 2-dichloroethane by ethane method and separating and recovering hydrogen chloride and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-27 CN claimed
CN-119178286-A System and method for preparing liquefied natural gas by double-circulation precooling mixed refrigerant 成都赛普瑞兴科技有限公司 2024-12-24 CN claimed
CN-119177844-A System and method for characterizing hydrocarbon-containing fluids 斯伦贝谢技术有限公司 2024-12-24 CN claimed
US-12168622-B2 Methods and systems for removing trichloroethane, trichloroethene, and 1,4-dioxane from contaminated water and wastewater ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-12-17 US claimed
CN-119118129-A Method for growing MXene material by gas phase method and application thereof 济南三川新材料科技有限公司 2024-12-13 CN claimed
WO-2024254035-A1 MICROENCAPSULATED PHEROMONE FORMULATIONS FMC Agricultural Solutions A/S (DK) 2024-12-12 WO claimed
EP-4469237-A1 METHOD AND APPARATUS FOR CRYOGENIC AND ENVIRONMENTAL CONTROLLED SPECIMEN HANDLING Expresslo LLC (US) 2024-12-04 EP claimed
EP-4466305-A1 DECOMPOSITION OF POLYOLEFINS Oxford University Innovation Limited (GB) 2024-11-27 EP claimed
CN-117379995-B Modified 4A molecular sieve membrane for selectively separating methane and ethane gas and preparation method and application thereof 中集安瑞科工程科技有限公司 2024-11-26 CN claimed
US-3939209-A AND VINYL CHLORIDE FROM ETHANE OR ETHYLENE AND ETHYL CHLORIDE AND METAL CHLORIDE OR OXYCHLORIDE THE LUMMUS COMPANY (US) 1976-02-17 US claimed
US-3937744-A MELTS OF METAL CHLORIDES THE LUMMUS COMPANY (US) 1976-02-10 US claimed
US-3936484-A Production of isocyanates from substituted ureas ATLANTIC RICHFIELD COMPANY (US) 1976-02-03 US claimed
US-3935177-A Polymerisation and copolymerisation of dienes BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US claimed
US-3933425-A Method of cleaning textiles HENKEL & CIE GMBH (DT) 1976-01-20 US claimed
US-3933030-A System for continuous monitoring of the density of cryogenic liquids via dielectric constant measurements EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-01-20 US claimed
US-3932552-A Integrated process for producing C2 hydrocarbons from carbon monoxide and hydrogen CONTINENTAL OIL COMPANY (US) 1976-01-13 US claimed
US-3932154-A Refrigerant apparatus and process using multicomponent refrigerant CHICAGO BRIDGE & IRON COMPANY (US) 1976-01-13 US claimed
US-3932356-A UNSATURATED POLYETHERESTER CONTAINING GLYCIDYL (METH)ACRYLATE OR ALLYL GLYCIDYL ETHER RESIDUES KANSAI PAINT COMPANY, LTD. (JA) 1976-01-13 US claimed
US-3932156-A Recovery of heavier hydrocarbons from natural gas HYDROCARBON RESEARCH, INC. (US) 1976-01-13 US claimed