Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424632 | 0.84 | BCHE (0.42) | NPC1HTTRAB9ARORCBCHE | |
| SCHEMBL421300 | 0.79 | RORC (0.36) | RORCBCHEABCB1GPR119ESR2 | |
| SCHEMBL25694403 | 0.77 | BCHE (0.37) | RORCBCHEABCB1GPR119ESR2 | |
| SCHEMBL421514 | 0.75 | BCHE (0.36) | NPC1HTTRAB9ARORCBCHE | |
| SCHEMBL26405191 | 0.74 | ABCB1 (0.37) | RORCBCHEABCB1GPR119ESR2 | |
| SCHEMBL498994 | 0.74 | NR1H2 (0.44) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL12562967 | 0.73 | HTT (0.33) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL28050021 | 0.72 | BCHE (0.41) | ALDH1A1MAPTMAPK1BCHEABCB1 | |
| SCHEMBL14260516 | 0.70 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL425376 | 0.70 | GLA (0.39) | L3MBTL1NR1H2TSHRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152313-A1 | SYNTHESIS OF AGELADINE A AND ANALOGS THEREOF | MACQUARIE UNIVERSITY (AU) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152313-A1 | SYNTHESIS OF AGELADINE A AND ANALOGS THEREOF | QDPR, ODC1, CROCC | NPC1 2239/4885ALDH1A1 45/4885MAPT 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.