Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929313 | 0.95 | CYP3A4 (0.46) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL14929493 | 0.95 | CYP3A4 (0.46) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL15159400 | 0.90 | CYP3A4 (0.41) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL9923593 | 0.89 | PDE4A (0.31) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL1252609 | 0.89 | CYP3A4 (0.52) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL1252938 | 0.89 | CYP3A4 (0.52) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL18234177 | 0.84 | CYP3A4 (0.46) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL15161165 | 0.84 | CYP3A4 (0.46) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL30417905 | 0.84 | CYP3A4 (0.48) | CYP3A4NPSR1ADORA2BUSP2MAPT | |
| SCHEMBL12158561 | 0.80 | CYP3A4 (0.55) | CYP3A4NPSR1ADORA2BUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420762-B2 | Silicone resin composition and a cured product thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20110147955-A1 | SILICONE RESIN COMPOSITION AND A CURED PRODUCT THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |