SCHEMBL14929313

SCHEMBL14929313

C=CCn1c(=O)n(CC=C)c(=O)n(CCC[Si](CO)(OC)OC)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
NPSR1 Q6W5P4 2/20 0.42
ADORA2B P29275 3/20 0.39
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 3/20 0.33
LMNA P02545 3/20 0.33
ADORA2A P29274 2/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
PLA2G4A P47712 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14929493 1.00 CYP3A4 (0.46) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL15159400 0.95 CYP3A4 (0.41) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL12565262 0.95 CYP3A4 (0.41) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL1252609 0.82 CYP3A4 (0.52) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL1252938 0.82 CYP3A4 (0.52) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL9923593 0.82 PDE4A (0.31) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL15159401 0.82 PDE4A (0.39) CYP3A4ADORA2BADORA2APDE4APDE4B
SCHEMBL1252565 0.81 CYP3A4 (0.50) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL17750829 0.81 CYP3A4 (0.50) CYP3A4NPSR1ADORA2BUSP2MAPT
SCHEMBL17928626 0.78 CYP3A4 (0.59) CYP3A4NPSR1ADORA2BUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9403967-B2 Curable resin composition, cured product thereof and photosemiconductor apparatus SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-02 US disclosed
US-9268227-B2 UV-curable adhesive silicone composition, UV-curable adhesive silicone composition sheet, optical semiconductor apparatus and method for manufacturing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-02-23 US disclosed
US-9147818-B2 Wavelength conversion sheet filled with large amount of phosphor, method of producing light emitting semiconductor device using the sheet, and light emitting semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-09-29 US disclosed
US-20150261088-A1 UV-CURABLE ADHESIVE SILICONE COMPOSITION, UV-CURABLE ADHESIVE SILICONE COMPOSITION SHEET, OPTICAL SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING THE SAME SHINETSU CHEMICAL CO (JP) 2015-09-17 US disclosed
US-20150245476-A1 SUBSTRATE AND SEMICONDUCTOR APPARATUS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-27 US disclosed
US-9117978-B2 Thermosetting silicone resin sheet and method for producing the same, and light-emitting apparatus using the thermosetting silicone resin sheet and method for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-25 US disclosed
US-8841689-B2 Heat-curable silicone resin sheet having phosphor-containing layer and phosphor-free layer, method of producing light emitting device utilizing same and light emitting semiconductor device obtained by the method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-23 US disclosed
US-20140175488-A1 HEAT-CURABLE SILICONE RESIN SHEET HAVING PHOSPHOR-CONTAINING LAYER AND WHITE PIGMENT-CONTAINING LAYER, METHOD OF PRODUCING LIGHT EMITTING DEVICE USING SAME AND ENCAPSULATED LIGHT EMITTING SEMICONDUCTOR DEVICE PRODUCED THEREBY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-26 US disclosed
US-20140124809-A1 THERMOSETTING SILICONE RESIN SHEET AND METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING APPARATUS USING THE THERMOSETTING SILICONE RESIN SHEET AND METHOD FOR PRODUCING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-08 US disclosed
US-20130183776-A1 UV-CURABLE ADHESIVE SILICONE COMPOSITION, UV-CURABLE ADHESIVE SILICONE COMPOSITION SHEET, OPTICAL SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-07-18 US disclosed
US-20130113008-A1 WAVELENGTH CONVERSION SHEET FILLED WITH LARGE AMOUNT OF PHOSPHOR, METHOD OF PRODUCING LIGHT EMITTING SEMICONDUCTOR DEVICE USING THE SHEET, AND LIGHT EMITTING SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-09 US disclosed