SCHEMBL9923593

SCHEMBL9923593

CO[Si](CO)(CCCn1c(=O)n(CCC[Si](OC)(OC)OC)c(=O)n(CCC[Si](OC)(OC)OC)c1=O)OC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12565262 0.89 CYP3A4 (0.41) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL15159401 0.87 PDE4A (0.39) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL155052 0.86 LMNA (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL1629496 0.85 PDE4A (0.31) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL12892325 0.83 PDE4A (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL14929493 0.82 CYP3A4 (0.46) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL14929313 0.82 CYP3A4 (0.46) PDE4AADORA2AADORA2BPDE4BPDE4C
Urea SCHEMBL1901789 0.81 PROKR1 (0.30) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL10015809 0.81 PDE4A (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL3402639 0.81 LMNA (0.32) PDE4AADORA2AADORA2BPDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209154-A1 POLYMER, DIELECTRIC FLUID, AND COOLING SYSTEM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-06-27 US disclosed
US-20180175090-A1 NEAR INFRARED ABSORBING COMPOSITION, FILM, NEAR INFRARED CUT FILTER, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2018-06-21 US disclosed
US-8420762-B2 Silicone resin composition and a cured product thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-16 US disclosed
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-20110147955-A1 SILICONE RESIN COMPOSITION AND A CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 PDE4A 4054/4885ADORA2A 4854/4885ADORA2B 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.