Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686152 | 0.89 | ALDH1A1 (0.46) | TSHRTHRBACHEKMT2AALDH1A1 | |
| SCHEMBL13585188 | 0.85 | TSHR (0.41) | TSHRTHRBACHE | |
| SCHEMBL14631623 | 0.85 | TSHR (0.41) | TSHRTHRBACHEALDH1A1MAPT | |
| SCHEMBL9776212 | 0.84 | TSHR (0.40) | TSHRTHRBALDH1A1MAPT | |
| SCHEMBL468011 | 0.82 | TSHR (0.50) | TSHRTHRBACHEMAPK1MEN1 | |
| SCHEMBL11406930 | 0.81 | TSHR (0.46) | TSHRTHRBACHEMAPK1MEN1 | |
| SCHEMBL2516798 | 0.81 | — | — | |
| SCHEMBL27525949 | 0.80 | TSHR (0.46) | TSHRTHRBACHEMAPK1MEN1 | |
| SCHEMBL18712265 | 0.80 | TSHR (0.48) | TSHRACHEALDH1A1 | |
| SCHEMBL11172572 | 0.80 | TSHR (0.38) | TSHRTHRBACHEMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110146516-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |