Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19679991 | 0.89 | THRB (0.54) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL12565645 | 0.89 | TSHR (0.48) | ALDH1A1MAPTTSHRTHRBKMT2A | |
| SCHEMBL28293945 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL79588 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL5534844 | 0.85 | THRB (0.62) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL15536700 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL14886410 | 0.84 | TSHR (0.53) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL17973526 | 0.84 | TSHR (0.50) | ALDH1A1MAPTTSHRTHRBNPSR1 | |
| Ammonia Solution, Strong SCHEMBL28294025 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRTHRBHSD17B10 | |
| SCHEMBL28099320 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRTHRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349700-A1 | POLYMER AND OTHER COMPOUNDS FUNCTIONALIZED WITH TERMINAL 1,1-DISUBSTITUTED ALKENE MONOMER(S) AND METHODS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |