Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.42 |
| ▸ | ATG7 | O95352 | 1/20 | 0.42 |
| ▸ | UBA7 | P41226 | 1/20 | 0.42 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.42 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566819 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL12652607 | 0.81 | NR2F2 (0.54) | CCNA2CDK2CDK5CDK5R1ADORA1 | |
| SCHEMBL32661823 | 0.81 | ADORA1 (0.65) | ADORA1SMN1; SMN2UBA6ATG7UBA7 | |
| SCHEMBL1798569 | 0.81 | ADORA1 (0.65) | ADORA1SMN1; SMN2UBA6ATG7UBA7 | |
| SCHEMBL12567124 | 0.81 | ABL1 (0.49) | NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL13773372 | 0.80 | BCHE (0.54) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL9587879 | 0.80 | ADORA3 (0.46) | CCNA2CDK2CDK5CDK5R1ADORA1 | |
| SCHEMBL12652428 | 0.80 | BCHE (0.43) | UBA6ATG7UBA7NAE1UBA3 | |
| SCHEMBL12567150 | 0.80 | BCHE (0.47) | SMN1; SMN2UBA6ATG7UBA7NAE1 | |
| Methyl Alcohol SCHEMBL9587418 | 0.79 | ADORA3 (0.46) | CCNA2CDK2CDK5CDK5R1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136834-A1 | INHIBITORS OF E1 ACTIVATING ENZYMES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136834-A1 | INHIBITORS OF E1 ACTIVATING ENZYMES | ECE1, RNASE1, RCE1 | CCNA2 200/4885CDK2 37/4885CDK5 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.