Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12546779 | 0.93 | GPR84 (0.36) | CASP3SENP7ESR1ESR2GPR84 | |
| SCHEMBL21704881 | 0.83 | GPR84 (0.37) | CASP3SENP7GPR84CYP1A2CYP3A4 | |
| SCHEMBL29152124 | 0.81 | CYP1A2 (0.55) | CASP3SENP7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17828550 | 0.77 | ABL1 (0.46) | GPR84CYP3A4SMN1; SMN2NPC1MAPT | |
| SCHEMBL5599147 | 0.76 | CYP1A2 (0.56) | CASP3SENP7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12546551 | 0.76 | ESR1 (0.38) | ESR1ESR2GPR84CYP1A2CYP3A4 | |
| SCHEMBL134695 | 0.75 | ACHE (0.47) | ABL1ABCB1BCRACACAALOX5 | |
| SCHEMBL24605401 | 0.74 | CYP11B1 (0.45) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12567615 | 0.73 | ESR1 (0.43) | ESR1ESR2TDP1 | |
| SCHEMBL19765465 | 0.73 | CYP1A2 (0.44) | CASP3SENP7ESR1ESR2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288016-B2 | Fused polycyclic compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110127908-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110127908-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | RPS19, RPL19, RNF168 | CASP3 2531/4885SENP7 1808/4885ESR1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.