Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.57 |
| ▸ | IGF1R | P08069 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376917 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL9001576 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL9586309 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL1315795 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL8937894 | 0.98 | KAT8 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL76664 | 0.94 | SKP2 (0.59) | KAT8IGF1RALOX15ESR1ADRA2A | |
| SCHEMBL11004150 | 0.88 | ALOX15 (0.61) | KAT8IGF1RALOX15ADRA2ASLC6A2 | |
| SCHEMBL11004234 | 0.88 | ALOX15 (0.61) | KAT8IGF1RALOX15ADRA2ASLC6A2 | |
| SCHEMBL1023135 | 0.86 | CNR1 (0.64) | ALOX15ADRA2ASLC6A2SLC6A3CYP3A4 | |
| SCHEMBL272900 | 0.86 | ALOX15 (0.58) | IGF1RALOX15ADRA2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419966-B1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC (CH) | 2020-03-25 | — | — | EP | disclosed |
| US-7879520-B2 | comprising binding resin (polystyrene) and charge control agent including azo-type iron complex salt; electrography; wear resistance; offset resistance | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1868038-B1 | Toner for developing electrostatic image and image formation process using it | ORIENT CHEMICAL IND (JP) | 2010-06-02 | — | — | EP | disclosed |
| US-20070292779-A1 | Toner for developing electrostatic image and image formation process using it | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2007-12-20 | — | — | US | disclosed |
| EP-1868038-A2 | Toner for developing electrostatic image and image formation process using it | Orient Chemical Industries, Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| EP-1678170-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | Yang Ji Chemical Company Ltd. (KR) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033104-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | YANG JI CHEMICAL COMPANY, LTD (KR) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | KAT8 2356/4885IGF1R 539/4885ALOX15 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.