Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283151 | 0.79 | ALDH1A1 (0.42) | TSHRGLAHTTL3MBTL1CNR2 | |
| SCHEMBL19465365 | 0.72 | ALDH1A1 (0.41) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL30395252 | 0.70 | ALDH1A1 (0.45) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL18066726 | 0.68 | ALDH1A1 (0.43) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL28775703 | 0.68 | ALDH1A1 (0.37) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL23515511 | 0.67 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL19465407 | 0.67 | MME (0.43) | ALDH1A1CYP3A4CA2KDM4E | |
| SCHEMBL29516457 | 0.67 | TSHR (0.39) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL868622 | 0.66 | TSHR (0.54) | TSHRGLAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL16411256 | 0.66 | L3MBTL1 (0.49) | HTTL3MBTL1ALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964741-B2 | Bibenzothiophene derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2011-06-21 | — | — | US | disclosed |
| US-7964741-B2 | Bibenzothiophene derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090292130-A1 | BIBENZOTHIOPHENE DERIVATIVES | US GOVERNMENT AS REPRESENTED BY SECRETARY OF ARMY (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090292130-A1 | BIBENZOTHIOPHENE DERIVATIVES | US GOVERNMENT AS REPRESENTED BY SECRETARY OF ARMY (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292130-A1 | BIBENZOTHIOPHENE DERIVATIVES | OCIAD2, OCIAD1, TBCD | TSHR 1728/4885GLA 4742/4885HTT 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.