Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645042 | 0.71 | USP2 (0.44) | PLA2G10PLA2G5 | |
| SCHEMBL28400350 | 0.69 | USP2 (0.44) | — | |
| SCHEMBL28610698 | 0.68 | KDM4E (0.36) | PLA2G10PLA2G5 | |
| SCHEMBL4931482 | 0.67 | PLA2G10 (0.34) | PLA2G10PLA2G5MIF | |
| SCHEMBL15397808 | 0.67 | PLA2G10 (0.34) | PLA2G10PLA2G5MIF | |
| SCHEMBL12806269 | 0.66 | PLA2G10 (0.31) | PLA2G10PLA2G5 | |
| SCHEMBL3324495 | 0.66 | KLK7 (0.36) | — | |
| SCHEMBL7132129 | 0.66 | KLK7 (0.36) | — | |
| SCHEMBL12805696 | 0.65 | MAPT (0.33) | — | |
| SCHEMBL6342104 | 0.65 | PLA2G10 (0.38) | PLA2G10PLA2G5MIFHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960578-B2 | Method for the synthesis of peptides without solvent | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-06-14 | — | — | US | disclosed |
| US-20100016631-A1 | METHOD FOR THE SYNTHESIS OF PEPTIDES WITHOUT SOLVENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016631-A1 | METHOD FOR THE SYNTHESIS OF PEPTIDES WITHOUT SOLVENT | NRDC, NPPA, RTF1 | PLA2G10 3498/4885PLA2G5 3825/4885NOD2 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.