Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12573099 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12573079 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12573072 | 0.94 | ALDH1A1 (0.35) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL15159450 | 0.94 | ALDH1A1 (0.35) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12633180 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12633182 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12633184 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12573110 | 0.80 | MAPK1 (0.51) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12632525 | 0.78 | ALDH1A1 (0.35) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL12632526 | 0.78 | ALDH1A1 (0.35) | ALDH1A1CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | disclosed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | C9, PROC, MLN | ALDH1A1 3071/4885CDK1 411/4885CCNB1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.