Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913206 | 0.92 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL14873540 | 0.92 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL12579920 | 0.92 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL12579207 | 0.90 | SLC29A1 (0.57) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL13467661 | 0.87 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL25098371 | 0.86 | HIF1A (0.67) | HIF1ASLC29A1 | |
| SCHEMBL12579620 | 0.84 | PRKAG1 (0.59) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL14713461 | 0.84 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL20626486 | 0.84 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL12579672 | 0.84 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069294-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | 中国医学科学院药物研究所 (CN) | 2011-06-16 | — | — | WO | disclosed |