Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579904 | 0.87 | PRKAG1 (0.59) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL12579620 | 0.87 | PRKAG1 (0.59) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL14873540 | 0.86 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL12579920 | 0.86 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL9913206 | 0.86 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL20626373 | 0.85 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1HIF1ATP53 | |
| SCHEMBL14714019 | 0.85 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1HIF1ATP53 | |
| SCHEMBL20626374 | 0.85 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1HIF1ATP53 | |
| SCHEMBL12579207 | 0.85 | SLC29A1 (0.57) | PRKAG1PRKAA1PRKAB1HIF1ASLC29A1 | |
| SCHEMBL14713372 | 0.85 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |