Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467664 | 0.83 | HIF1A (0.60) | SLC29A1 | |
| SCHEMBL23982263 | 0.83 | ADORA3 (0.67) | SLC29A1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7737737 | 0.83 | ADORA3 (0.67) | SLC29A1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7737742 | 0.83 | ADORA3 (0.67) | SLC29A1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL14713414 | 0.83 | ADORA3 (0.67) | ADORA2AADORA3ADORA2BSLC6A2ADORA1 | |
| SCHEMBL20626493 | 0.83 | ADORA3 (0.67) | ADORA2AADORA3ADORA2BSLC6A2ADORA1 | |
| SCHEMBL14714110 | 0.83 | ADORA3 (0.67) | ADORA2AADORA3ADORA2BSLC6A2ADORA1 | |
| SCHEMBL20626492 | 0.83 | ADORA3 (0.67) | ADORA2AADORA3ADORA2BSLC6A2ADORA1 | |
| SCHEMBL24021943 | 0.81 | SLC29A1 (0.65) | SLC29A1ADORA2AADORA3ADORA1 | |
| SCHEMBL13467562 | 0.81 | SLC29A1 (0.54) | SLC29A1ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069294-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | 中国医学科学院药物研究所 (CN) | 2011-06-16 | — | — | WO | disclosed |