Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25098371 | 0.88 | HIF1A (0.67) | HIF1ASLC29A1 | |
| SCHEMBL13467566 | 0.84 | HIF1A (0.59) | HIF1ASLC29A1 | |
| SCHEMBL12579974 | 0.83 | SLC29A1 (0.54) | SLC29A1 | |
| SCHEMBL548569 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL21011280 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL548570 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL23982373 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL6267085 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL6267089 | 0.83 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL20626493 | 0.83 | ADORA3 (0.67) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |