Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL11902971 | 0.95 | LTB4R (0.41) | LTB4RLTB4R2FFAR4CYSLTR2CYSLTR1 | |
| SCHEMBL12377694 | 0.94 | LTB4R (0.42) | LTB4RLTB4R2CYSLTR2CYSLTR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL11902973 | 0.93 | LTB4R (0.37) | LTB4RLTB4R2FFAR4CYSLTR2CYSLTR1 | |
| Acetic Acid SCHEMBL1258679 | 0.92 | LTB4R (0.41) | LTB4RLTB4R2CYSLTR2CYSLTR1MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL442746 | 0.91 | LTB4R (0.36) | LTB4RLTB4R2FFAR4CYSLTR2CYSLTR1 | |
| Acetic Acid SCHEMBL1258682 | 0.90 | LTB4R (0.40) | LTB4RLTB4R2CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL18803960 | 0.82 | LMNA (0.42) | LTB4RLTB4R2CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL18803958 | 0.81 | FOLH1 (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL12377692 | 0.81 | MAPT (0.40) | MEN1KMT2AHIF1ALMNAALDH1A1 | |
| SCHEMBL12377705 | 0.81 | MEN1 (0.40) | MEN1KMT2ALMNANPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467478-A1 | STABILIZATION OF ENZYMES USING STABLE COENZYMES | F. Hoffmann-La Roche AG (CH) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011020856-A1 | STABILIZATION OF ENZYMES USING STABLE COENZYMES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-24 | — | — | WO | disclosed |