SCHEMBL1259

SCHEMBL1259

O=C(OO)c1cccc(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.64
KDM4E B2RXH2 2/20 0.55
GAA P10253 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 2/20 0.53
USP2 O75604 1/20 0.53
ALOX15 P16050 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TDP1 Q9NUW8 1/20 0.50
RAB9A P51151 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CHRM2 P08172 1/20 0.49
CHRM4 P08173 1/20 0.49
CHRM1 P11229 1/20 0.49
CHRM3 P20309 1/20 0.49
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
NPC1 O15118 1/20 0.47
KCNQ3 O43525 1/20 0.47
KCNQ2 O43526 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4370629 1.00 PARP1 (0.64) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL29351761 1.00 PARP1 (0.64) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL28819341 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL11613703 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL1471300 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
Hydrochloric Acid SCHEMBL8503466 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL11105533 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL31245780 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL5484641 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
Hydrogen Peroxide SCHEMBL8452315 0.98 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 127643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478295-B1 SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES PHARMACOSMOS HOLDING AS (DK) 2026-05-27 EP claimed
CN-122080353-A Bio-based polyol, preparation method thereof, polyurethane composition, polyurethane foam and refrigeration equipment 2026-05-26 CN claimed
CN-122079864-A Dispiro naphthalene-1, 3' -indene-1 ',2' -pyrrolidone derivative, synthesis method and application 2026-05-26 CN claimed
CN-122079974-A Synthesis method of two methylsulfonyl phenyl oxadiazole active esters 2026-05-26 CN claimed
CN-121122800-B High-stability resistance paste and preparation method thereof Changchun Changguang Qichen Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122079849-A Slave dimension lattice in the mother liquor of the statin method for efficiently recycling vildagliptin 2026-05-26 CN claimed
CN-122079818-A Open chain imine axial chiral compound and synthesis method thereof 2026-05-26 CN claimed
CN-122080597-A Density-adjustable degradable temporary plugging material raw material composition, degradable temporary plugging material, preparation method and application thereof 2026-05-26 CN claimed
CN-122085597-A Photoresist for capacitive touch sensor and preparation process thereof 2026-05-26 CN claimed
CN-122079922-A Synthesis method of two bis (methylsulfonyl) phenyl oxadiazoles 2026-05-26 CN claimed
US-4011169-A USING AN ENZYME AND AMINATED POLYSACCHARIDE THE PROCTER & GAMBLE COMPANY (US) 1977-03-08 US claimed
US-4006142-A Preparation of methyl-3-(2-quinoxalinylmethylene)carbazate-N1,N4 -dioxide PFIZER INC. (US) 1977-02-01 US claimed
US-4003922-A Synthesis of cis-1,4-cyclohexadiene dioxide BRISTOL-MYERS COMPANY (US) 1977-01-18 US claimed
US-4001131-A BLEACHING THE PROCTER & GAMBLE COMPANY (US) 1977-01-04 US claimed
US-3989684-A OXIDIZING A THIOCARBAMATE WITH PERACETIC ACID OR M-CHLOROPEROXYBENZOIC ACID STAUFFER CHEMICAL COMPANY (US) 1976-11-02 US claimed
US-3978053-A Process for producing cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-08-31 US claimed
US-3976636-A Process and compounds THE UPJOHN COMPANY (US) 1976-08-24 US claimed
US-3954848-A Process for producing N-phosphonomethyl glycine MONSANTO COMPANY (US) 1976-05-04 US claimed
US-3950404-A Method for preparation of sulfinic acids GESELLSCHAFT FUR KERNFORSCHUNG MBH (DT) 1976-04-13 US claimed
US-3946065-A Production of cyclopentane derivatives SUMITOMO CHEMICAL CO., LTD. (JA) 1976-03-23 US claimed