SCHEMBL5484641

SCHEMBL5484641

O=C(OO)c1cccc(Cl)c1.[NaH]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.62
KDM4E B2RXH2 2/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 2/20 0.51
USP2 O75604 1/20 0.51
ALOX15 P16050 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TDP1 Q9NUW8 1/20 0.49
RAB9A P51151 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRM3 P20309 1/20 0.48
ERCC5 P28715 1/20 0.47
FEN1 P39748 1/20 0.47
NPC1 O15118 1/20 0.46
KCNQ3 O43525 1/20 0.46
KCNQ2 O43526 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1259 0.98 PARP1 (0.64) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL4370629 0.98 PARP1 (0.64) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL29351761 0.98 PARP1 (0.64) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL28819341 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL31245780 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
Hydrochloric Acid SCHEMBL8503466 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL11105533 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL11613703 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
Water SCHEMBL16144828 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1
SCHEMBL1471300 0.96 PARP1 (0.62) PARP1KDM4EGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102964337-A Production method of high-optical-purity esomeprazole NANJING XUN AN PHARMACEUTICAL TECHNOLOGY CO LTD 2013-03-13 CN claimed
US-20070166339-A1 Skin Whitening Methods and Compositions Based on Zeolite - Active Oxygen Donor Complexes BIODERM RESEARCH (US) 2007-07-19 US claimed
EP-3325472-A1 SUBSTITUIERTED FURANO-/THIENOCYCLOALKYLAMINO-2-PYRIMIDINE DERIVATIVES AND USE THEREOF FOR CONTROLLING UNDESIRED PLANT GROWTH Bayer CropScience AG (DE) 2018-05-30 EP disclosed
CN-102964337-A Production method of high-optical-purity esomeprazole NANJING XUN AN PHARMACEUTICAL TECHNOLOGY CO LTD 2013-03-13 CN disclosed
US-20070166339-A1 Skin Whitening Methods and Compositions Based on Zeolite - Active Oxygen Donor Complexes BIODERM RESEARCH (US) 2007-07-19 US disclosed
CN-1322713-A Prepn of m-chlorobenzoyl hydroperoxide YIXING CITY CHEMICAL REAGENT P (CN) 2001-11-21 CN disclosed
US-4163743-A Beta-lactams, their production from azetidine carboxylic acids, intermediates thereto and derivatives thereof RESEARCH CORPORATION (US) 1979-08-07 US disclosed