Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351761 | 1.00 | PARP1 (0.64) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL1259 | 1.00 | PARP1 (0.64) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL28819341 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL11613703 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL1471300 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8503466 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL11105533 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL31245780 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL5484641 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 | |
| Hydrogen Peroxide SCHEMBL8452315 | 0.98 | PARP1 (0.62) | PARP1KDM4EGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964978-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2024-04-23 | — | — | US | disclosed |
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-106588745-B | A kind of intermediate and its preparation method and application of benzo alkene fluorine bacterium azoles | 杭州百昂锐地科技有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-106588668-A | 2-bromine-5-nitro-1,2,3,4-tetrahydro-1,4-methano-naphthalene-9-phenol and preparation method thereof | 杭州百昂锐地科技有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-106588745-A | Intermediate of benzovindiflupyr and preparation method and application thereof | 杭州百昂锐地科技有限公司 | 2017-04-26 | — | — | CN | disclosed |
| EP-2049534-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS | Glaxo Group Limited (GB) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008009735-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964978-B2 | Modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | PARP1 1606/4885KDM4E 3884/4885GAA 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.