Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259082 | 0.81 | KDM4E (0.63) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL13596324 | 0.81 | KDM4E (0.47) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6908359 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6914098 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6915538 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6916673 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6915536 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1TPMTMETAP2CSNK2A1 | |
| SCHEMBL6910129 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL8092458 | 0.79 | KDM4E (0.45) | KDM4ECA1CA2MMP1MMP2 | |
| SCHEMBL6914424 | 0.79 | KDM4E (0.61) | KDM4ECA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| WO-2011016581-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | HRH1, HK1, HMOX1 | KDM4E 2710/4885CA1 326/4885CA2 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.