Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.74 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259094 | 1.00 | FAAH (0.74) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL12013888 | 0.97 | FAAH (0.72) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL12013735 | 0.95 | FAAH (0.81) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL12013727 | 0.89 | FAAH (0.69) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL1259408 | 0.89 | FAAH (0.69) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL1259405 | 0.89 | FAAH (0.69) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17295326 | 0.88 | FAAH (0.84) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17295325 | 0.88 | FAAH (0.84) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17302128 | 0.88 | FAAH (0.89) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL12013229 | 0.87 | FAAH (0.72) | FAAHS1PR1S1PR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| US-20110039849-A1 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2011-02-17 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039849-A1 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | IRF3, GDI2, TLR5 | FAAH 4487/4885S1PR1 4789/4885S1PR3 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.