Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173514 | 1.00 | OPRD1 (0.34) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL1173160 | 1.00 | OPRD1 (0.34) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL2585666 | 0.90 | OPRD1 (0.33) | OPRD1IDO1TDO2 | |
| SCHEMBL1173154 | 0.87 | OPRD1 (0.34) | OPRD1 | |
| SCHEMBL1173155 | 0.87 | OPRD1 (0.34) | OPRD1 | |
| SCHEMBL12273743 | 0.87 | OPRD1 (0.33) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL12273744 | 0.87 | OPRD1 (0.33) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL2591849 | 0.85 | PGR (0.35) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL2591851 | 0.85 | PGR (0.35) | OPRD1PGRIDO1TDO2 | |
| SCHEMBL1173264 | 0.83 | OPRD1 (0.33) | OPRD1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020806-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-24 | — | — | WO | disclosed |