Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TNKS | O95271 | 2/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399890 | 0.85 | GUSB (0.61) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL30397301 | 0.84 | NPBWR1 (0.73) | KDM4ENPBWR1MAPTNPC1RAB9A | |
| SCHEMBL2245293 | 0.84 | NPBWR1 (0.73) | KDM4ENPBWR1MAPTNPC1RAB9A | |
| SCHEMBL2991045 | 0.83 | TNKS (0.73) | GUSBHPGDTNKSTNKS2NLRP3 | |
| SCHEMBL2250346 | 0.82 | NPBWR1 (0.60) | KDM4ENPBWR1MAPTNPC1RAB9A | |
| SCHEMBL2685097 | 0.80 | GUSB (0.70) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL12591987 | 0.80 | GUSB (0.70) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL11243512 | 0.80 | GUSB (0.70) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL4090569 | 0.80 | GUSB (0.70) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL30665826 | 0.79 | TNKS (0.75) | GUSBHPGDTNKSTNKS2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117659-A1 | QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES | Life Technologies Corporation (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110117659-A1 | QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES | Life Technologies Corporation (US) | 2011-05-19 | — | — | US | disclosed |
| US-7816527-B2 | Quinazoline-containing kits for labeling aldehyde or ketone moieties | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816527-B2 | Quinazoline-containing kits for labeling aldehyde or ketone moieties | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |