Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358025 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL1358023 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL1358127 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL3782952 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL28429886 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL1259309 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL28429888 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL3782955 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL1358131 | 1.00 | GPR84 (0.56) | GPR84FFAR4FFAR1PPARGPPARD | |
| SCHEMBL1358698 | 0.93 | GPR84 (0.50) | GPR84FFAR4FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632191-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2020-04-28 | — | — | US | disclosed |
| EP-3124491-B1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS AND VACCINE COMPOSITIONS AS WELL AS PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INFECTIOUS DISEASE RES INST (US) | 2019-10-30 | — | — | EP | disclosed |
| US-20180028649-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2018-02-01 | — | — | US | disclosed |
| US-9814772-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170182155-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RES INST (US) | 2017-06-29 | — | — | US | disclosed |
| EP-3124491-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS AND VACCINE COMPOSITIONS CONTAINING THEM | Infectious Disease Research Institute (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9480740-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2016-11-01 | — | — | US | disclosed |
| EP-2437753-B1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS AND VACCINE COMPOSITIONS CONTAINING THEM | INFECTIOUS DISEASE RES INST (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9309276-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-9259476-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-20140322268-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2014-10-30 | — | — | US | disclosed |
| US-8809285-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2014-08-19 | — | — | US | disclosed |
| US-8722064-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2014-05-13 | — | — | US | disclosed |
| US-20140011987-A1 | Synthetic Lipid A Derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-01-09 | — | — | US | disclosed |
| US-8563523-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2011014771-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2011-02-03 | — | — | WO | disclosed |
| US-20100310602-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011987-A1 | Synthetic Lipid A Derivative | DDOST, STT3A, UGCG | GPR84 925/4885FFAR4 110/4885FFAR1 136/4885 |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | GPR84 1980/4885FFAR4 239/4885FFAR1 379/4885 |
| US-20140322268-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 1934/4885FFAR4 571/4885FFAR1 925/4885 |
| US-10632191-B2 | Synthetic glucopyranosyl lipid adjuvants | B3GAT3, GLA, LGALS8 | GPR84 2007/4885FFAR4 577/4885FFAR1 958/4885 |
| US-20100310602-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 1934/4885FFAR4 571/4885FFAR1 925/4885 |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | GPR84 925/4885FFAR4 110/4885FFAR1 136/4885 |
| US-20180028649-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 2007/4885FFAR4 577/4885FFAR1 958/4885 |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | GPR84 925/4885FFAR4 110/4885FFAR1 136/4885 |
| US-20170182155-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 1934/4885FFAR4 571/4885FFAR1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.