SCHEMBL12593201

SCHEMBL12593201

CCCCCCn1c2cc(C)ccc2c2ccc(C)cc21

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.55
PSEN1 P49768 15/20 0.54
PSEN2 P49810 15/20 0.54
APH1B Q8WW43 15/20 0.54
NCSTN Q92542 15/20 0.54
APH1A Q96BI3 15/20 0.54
PSENEN Q9NZ42 15/20 0.54
PGR P06401 1/20 0.47
RORA P35398 1/20 0.47
RORC P51449 1/20 0.47
RORB Q92753 1/20 0.47
CNR2 P34972 1/20 0.46
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12593198 1.00 TLR8 (0.55) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL12593197 0.98 TLR8 (0.56) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL18947670 0.93 RORA (0.53) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL12379845 0.88 PSEN1 (0.48) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL13125230 0.86 RORA (0.58) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL12593271 0.86 RORA (0.63) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL278915 0.86 TLR8 (0.44) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL15396934 0.86 RORA (0.61) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL12593202 0.86 RORA (0.61) TLR8PSEN1PSEN2APH1BNCSTN
SCHEMBL12284774 0.86 RORA (0.61) TLR8PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed
US-20110121278-A1 SOLUTION COMPOSITION AND POLYMER LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL CO., LTD. (JP) 2011-05-26 US disclosed
US-7910025-B2 Solution composition and polymer light-emitting device SUMITOMO CHEMICAL CO., LTD. (JP) 2011-03-22 US disclosed
US-20080061673-A1 Solution Composition And Polymer Light-Emitting Device SUMITOMO CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed