Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 3/20 | 0.61 |
| ▸ | RORC | P51449 | 3/20 | 0.61 |
| ▸ | RORB | Q92753 | 3/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.54 |
| ▸ | CNR2 | P34972 | 8/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL804880 | 1.00 | RORA (0.61) | RORARORCRORBPGRTLR8 | |
| SCHEMBL14261677 | 1.00 | RORA (0.61) | RORARORCRORBPGRTLR8 | |
| SCHEMBL12593202 | 1.00 | RORA (0.61) | RORARORCRORBPGRTLR8 | |
| SCHEMBL13503151 | 1.00 | RORA (0.61) | RORARORCRORBPGRTLR8 | |
| SCHEMBL15396934 | 1.00 | RORA (0.61) | RORARORCRORBPGRTLR8 | |
| SCHEMBL12593203 | 0.98 | RORA (0.63) | RORARORCRORBPGRTLR8 | |
| SCHEMBL13125230 | 0.97 | RORA (0.58) | RORARORCRORBPGRTLR8 | |
| SCHEMBL6365787 | 0.94 | RORA (0.56) | RORARORCRORBPGRTLR8 | |
| SCHEMBL14029768 | 0.94 | PGR (0.56) | RORARORCRORBPGRTLR8 | |
| SCHEMBL12374352 | 0.93 | RORA (0.69) | RORARORCRORBPGRTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | disclosed |